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Article

Manipulation of outer root sheath cell survival perturbs the hair-growth cycle.

The EMBO journal - 1 Jul 1999

Pena J C, Kelekar A, Fuchs E V, Thompson C B

Abstract excerpt

Transgenic mice that overexpress the anti-apoptotic gene bcl-xL under the control of the keratin 14 promoter have significantly shorter hair than non-transgenic littermates. The deficit in hair length correlated with a decrease in the duration of anagen, the growth phase of the hair cycle. A prolongation in telogen, the resting phase of the hair cycle, was also observed in adult animals. In the developing hair...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10393176
DOI: 10.1093/emboj/18.13.3596
PMCID: PMC1171438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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