Article
Hair cycle control by estrogens: catagen induction via estrogen receptor (ER)-alpha is checked by ER beta signaling.
Endocrinology - 1 Mar 2005
Ohnemus Ulrich, Uenalan Murat, Conrad Franziska, Handjiski Bori, Mecklenburg Lars, Nakamura Motonobu, Inzunza José, Gustafsson Jan-Ake, Paus Ralf
Abstract excerpt
Although 17beta-estradiol (E2) is recognized as a potent hair growth modulator, our knowledge of estrogen function, signaling, and target genes in hair biology is still very limited. Between the two recognized estrogen receptors (ERs), ER alpha and ER beta, only ER alpha had been detected in murine skin. Here we show that ER alpha, ER beta, and ER beta ins are all expressed throughout the murine hair cycle, both...
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