Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes.

Diabetes - 1 Jul 1999

Vaarala O, Knip M, Paronen J, Hämäläinen A M, Muona P, Väätäinen M, Ilonen J, Simell O, Akerblom H K

Abstract excerpt

Insulin autoantibodies (IAAs) often appear as the first sign of islet cell autoimmunity in prediabetic children. Because cow's milk contains bovine insulin, we followed the development of insulin-binding antibodies in children fed with cow's milk formula. Bovine insulin- and human insulin-binding antibodies by enzyme immunoassay and IAA by radioimmunoassay were analyzed in 200 infants carrying HLA-DQB1*0302 but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen-Antibody Reactions
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Finland

Share to Immunization

Share to Immunoglobulin G

Share to Infant, Newborn

Share to Insulin

Source

Identifiers

PMID: 10389843
DOI: 10.2337/diabetes.48.7.1389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes.PMID 10389843Read ↗

Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group.Semantic proximity Read ↗

Short-term exclusive breastfeeding predisposes young children with increased genetic risk of Type I diabetes to progressive beta-cell autoimmunity.Semantic proximity Read ↗

Enhanced levels of cow's milk antibodies in infancy in children who develop type 1 diabetes later in childhood.Semantic proximity Read ↗

Significance of cow's milk protein antibodies as risk factor for childhood IDDM: interactions with dietary cow's milk intake and HLA-DQB1 genotype. Childhood Diabetes in Finland Study Group.Semantic proximity Read ↗

High Concentrations of Immunoglobulin G Against Cow Milk Proteins and Frequency of Cow Milk Consumption Are Associated With the Development of Islet Autoimmunity and Type 1 Diabetes-The Trial to Reduce Insulin-dependent Diabetes Mellitus (IDDM) in the Genetically at Risk (TRIGR) Study.Semantic proximity Read ↗

Dietary intervention in infancy and later signs of beta-cell autoimmunity.Semantic proximity Read ↗

Early infant feeding and risk of developing type 1 diabetes-associated autoantibodies.Semantic proximity Read ↗

The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.Semantic proximity Read ↗

First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study.Semantic proximity Read ↗

Cow's milk and immune-mediated diabetes.Semantic proximity Read ↗

The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young.Semantic proximity Read ↗

Prevalence and fate of type 1 diabetes-associated autoantibodies in cord blood samples from newborn infants of non-diabetic mothers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.