A combination of the effects of rare genotypes at the XK and KEL blood group loci results in absence of Kell system antigens from the red blood cells.

Article

A combination of the effects of rare genotypes at the XK and KEL blood group loci results in absence of Kell system antigens from the red blood cells.

Blood - 15 Nov 1996

Daniels G L, Weinauer F, Stone C, Ho M, Green C A, Jahn-Jochem H, Offner R, Monaco A P

Abstract excerpt

The 22 antigens of the Kell blood group system are located on a red blood cell (RBC) membrane glycoprotein that shows sequence homology with a family of metalloendopeptidases. Expression of the Kell system antigens is partially governed by XK, an X-linked gene that encodes the Kx protein; absence...

Topics

Erythrocyte Membrane
Female
Genotype
Humans
Isoantibodies
Kell Blood-Group System
Male
Membrane Glycoproteins
Metalloendopeptidases
Middle Aged
Pedigree

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