Article
Thalassemia and malaria: new insights into an old problem.
Proceedings of the Association of American Physicians - 1 Jan 2000
Clegg J B, Weatherall D J
Abstract excerpt
The hemoglobinopathies are probably the world's most common genetic diseases: The World Health Organization has estimated that at least 5% of the population are carriers for one or other of the most serious forms, the alpha- and beta-thalassemias and the structural variant hemoglobins S, C, and E, which are found at polymorphic frequencies in many countries. All these hemoglobinopathies are believed to provide...
Topics
- Africa
- Anemia, Sickle Cell
- Asia, Southeastern
- Child
- Child, Preschool
- Ethnicity
- Europe
- Evolution, Molecular
- Genetic Predisposition to Disease
- Genotype
- Globins
- Hemoglobins