Article
Evolution of neurofilament subtype accumulation in axons following diffuse brain injury in the pig.
Journal of neuropathology and experimental neurology - 1 Jun 1999
Chen X H, Meaney D F, Xu B N, Nonaka M, McIntosh T K, Wolf J A, Saatman K E, Smith D H
Abstract excerpt
Although accumulation of neurofilament (NF) proteins in axons has been recognized as a prominent feature of brain trauma, the temporal course of the accumulation of specific NF subtypes has not been well established. In the present study, 17 miniature swine were subjected to nonimpact inertial brain injury. At 3 hours (h), 6 h, 24 h, 3 days, 7 days, and 10 days post-trauma, immunohistochemical analysis was...
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