Article
[The central melanocortin system and its role in energy homeostasis].
Annales d'endocrinologie - 1 Mar 1999
Cone R D
Abstract excerpt
Obesity is an important health concern, and the central melanocortin system is likely to play an important role in both normal regulation of energy homeostasis as well as genetic predisposition to obesity. Three different mouse models of obesity have been created by virtue of mutations which alter the function of the melanocortin system, and a rare form of human obesity has been characterized in two families with...
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