Article
The role of leptin-melanocortin system and human weight regulation: lessons from experiments of nature.
Annals of the Academy of Medicine, Singapore - 1 Jan 2009
Lee Yung Seng
Abstract excerpt
INTRODUCTION: Common obesity is a multi-factorial trait, contributed by the "obesogenic" environment of caloric abundance and increasing automation, sedentary lifestyle and an underlying genetic susceptibility. There have been major advances in the past decade in our understanding of the human weight regulation mechanism and pathogenesis of obesity, abetted by discoveries of genetic defects which lead to human...
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