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Article

An HLB-B null allele (B*0808N) caused by a nucleotide deletion in exon 3, found in the family of a bone marrow transplant recipient.

Tissue antigens - 1 Jan 2000

Carter V, Dunn P P, Cavanagh G, Day S, Ross J, Chapman C

Abstract excerpt

We have identified a variant HLA-B allele, B*0808N, segregating through two generations of healthy individuals, whilst HLA typing the family of a bone marrow patient. Serological typing identified a disparity between the father (A1, A3 B7 DR7) and the brother (A1, A2 B56 DR1, DR7) of the patient. Low/medium resolution polymerase chain reaction using sequence-specific primers (PCR-SSP) revealed a B*08 allele...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Bone Marrow Transplantation
Codon, Terminator
DNA Primers
Exons
Frameshift Mutation
HLA-B8 Antigen
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymerase Chain Reaction

Sequence Deletion

Source

Identifiers

PMID: 10703611
DOI: 10.1034/j.1399-0039.2000.550111.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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