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Article

Cyclin-D1 expression in human renal-cell carcinoma

21 Jun 1999

Abstract excerpt

Cyclin-D1 over-expression represents one of several common alterations in the G1-S transition associated with malignancies. Conclusive evidences indicate that cyclin D1 is a proto-oncogene and the gene is amplified or rearranged in different tumour types. Since very little is known about aberrations in the G1-S transition in human renal-cell carcinoma (RCC), we have characterized the expression of cyclin D1 in 80...

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PMID: 10371345
DOI: 10.1002/(sici)1097-0215(19990621)84:3<268::aid-ijc12>3.0.co;2-8

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