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Overexpression of CYP11A1 recovers cell cycle distribution in renal cell carcinoma Caki-1

1 Oct 2022

Abstract excerpt

BACKGROUND: Clear cell renal carcinoma is commonly known for its metastasis propensity to outspread to other organs and is asymptomatic in the early stage. Recent studies have shown that deficiencies in CYP11A1 expression can lead to fatal adrenal failure if left untreated and are associated with downstream regulation in various cancer types. However, the molecular mechanisms of CYP11A1 and kidney cancer...

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PMID: 36182900
DOI: 10.1186/s12935-022-02726-4

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