Article
Expression of sex hormone-binding globulin exon 7 splicing variant mRNA in secondary spreading lesions of gynecological cancers.
The Journal of steroid biochemistry and molecular biology - 1 Feb 1999
Misao R, Iwagaki S, Fujimoto J, Nakanishi Y, Sun W S, Tamaya T
Abstract excerpt
This study was designed to determine the clinical implications of intracellular expression of sex hormone-binding globulin (SHBG) wild-type and exon 7 splicing variant mRNAs in secondary spreading lesions of gynecologic cancers using the reverse transcription-polymerase chain reaction-Southern blot and DNA sequencing analyses. Compared with primary cancers, a relative increase in SHBG variant mRNA to wild-type...
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