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Article

Some statistical improvements for estimating population size and mutation rate from segregating sites in DNA sequences.

Theoretical population biology - 1 Jun 1999

Klein E K, Austerlitz F, Larédo C

Abstract excerpt

In population genetics, under a neutral Wright-Fisher model, the scaling parameter straight theta=4Nmu represents twice the average number of new mutants per generation. The effective population size is N and mu is the mutation rate per sequence per generation. Watterson proposed a consistent estimator of this parameter based on the number of segregating sites in a sample of nucleotide sequences. We study the...

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Identifiers

PMID: 10366549
DOI: 10.1006/tpbi.1998.1401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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