Article
Histological damage in chronic hepatitis C is not related to the extent of infection in the liver.
The American journal of pathology - 1 Jun 1999
Rodríguez-Iñigo E, Bartolomé J, de Lucas S, Manzarbeitia F, Pardo M, Arocena C, Gosálvez J, Oliva H, Carreño V
Abstract excerpt
It has not been completely elucidated whether the liver injury induced by the hepatitis C virus (HCV) is due to direct cytopathic damage or to an immune-mediated response against HCV-infected hepatocytes. In this work, we have determined the percentage of HCV-infected hepatocytes, the histological activity index, and the viremia levels in chronically HCV-infected patients with different grades of liver injury to...
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