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Article

High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.

BMC medical genetics - 30 Nov 2010

Papp Janos, Kovacs Marietta Eva, Solyom Szilvia, Kasler Miklos, Børresen-Dale Anne-Lise, Olah Edith

Abstract excerpt

BACKGROUND: Peutz-Jeghers syndrome (PJS) is a rare autosomal dominantly inherited disease characterized by gastrointestinal hamartomatous polyposis and mucocutaneous pigmentation. The genetic predisposition for PJS has been shown to be associated with germline mutations in the STK11/LKB1 tumor suppressor gene. The aim of the present study was to characterize Hungarian PJS patients with respect to germline...

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Source

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Identifiers

PMID: 21118512
DOI: 10.1186/1471-2350-11-169
PMCID: PMC3012662

Genes

STK11
GPX4
SBNO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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