Article
Dopamine D3 receptor gene polymorphism and alcohol dependence: relation to personality rating.
Psychiatric genetics - 1 Mar 1999
Thome J, Weijers H G, Wiesbeck G A, Sian J, Nara K, Böning J, Riederer P
Abstract excerpt
Hereditary dopaminergic mechanisms have been implicated in the aetiology of alcoholism. For this study, the distribution of a dopamine D3 receptor gene polymorphism (Ball) has been investigated in patients suffering from alcohol dependence, and compared with non-dependent controls. The allele A1 occurred significantly more frequently among patients compared to controls. Patients with the genotype A1/A2 showed...
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