Article
Functional analysis of HO gene in delayed homothallism in Saccharomyces cerevisiae wy2.
Yeast (Chichester, England) - 1 Apr 1999
Ekino K, Kwon I, Goto M, Yoshino S, Furukawa K
Abstract excerpt
Saccharomyces cerevisiae wy2 exhibits a novel life cycle, with delayed homothallism caused by a defective HO gene. In this strain, gradual diploidization occurs during successive subcultures. Three amino acids of wy2 HO were different from those of wild-type (wt) HO, which included a nonsense mutation (TAG) from Trp-292 and two amino acid changes of His-475 to Leu and Glu-530 to Lys. The ho gene of heterothallic...
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