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Article

Conversion of homothallic yeast to heterothallism through HO gene disruption.

Current genetics - 1 Jan 1993

van Zyl W H, Lodolo E J, Gericke M

Abstract excerpt

A simple method was developed for the conversion of homothallic Saccharomyces cerevisiae yeast strains to heterothallism through HO gene disruption. An integrative ho::neo disrupted allele was constructed by cloning a dominant selectable marker, the bacterial neo gene, within the HO gene. Transformation of a homothallic diploid S. cerevisiae strain with plasmid DNA containing the ho::neo allele yielded...

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Identifiers

PMID: 8385580
DOI: 10.1007/BF00310889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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