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Atypical Chronic Lymphocytic Leukemia—The Current Status

5 Sept 2023

Abstract excerpt

A diagnosis of typical chronic lymphocytic leukemia (CLL) requires the presence of ≥5000 clonal B-lymphocytes/μL, the coexistence of CD19, CD20, CD5, and CD23, the restriction of light chain immunoglobulin, and the lack of expression of antigens CD22 and CD79b. Atypical CLL (aCLL) can be distinguished from typical CLL morphologically and immunophenotypically. Morphologically atypical CLL cells have been defined...

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PMID: 37760396
DOI: 10.3390/cancers15184427

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