Article
Complementarity-determining region (CDR) implantation: a theme of recombination.
Immunotechnology : an international journal of immunological engineering - 1 Mar 1999
Söderlind E, Ohlin M, Carlsson R
Abstract excerpt
A novel technology in the area of antibody engineering has been developed which allows for the creation of new types of antibody molecules. It is called complementarity-determining region (CDR) implantation and permits the random combination of CDR sequences formed in vivo into a single master framework. Thus, totally new gene combinations can be produced and used in selection processes. The result is a genetic...
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