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Article

PBP5, PBP6 and DacD play different roles in intrinsic β-lactam resistance of Escherichia coli.

Microbiology (Reading, England) - 1 Sept 2011

Sarkar Sujoy Kumar, Dutta Mouparna, Chowdhury Chiranjit, Kumar Akash, Ghosh Anindya S

Abstract excerpt

Escherichia coli PBP5, PBP6 and DacD, encoded by dacA, dacC and dacD, respectively, share substantial amino acid identity and together constitute ~50 % of the total penicillin-binding proteins of E. coli. PBP5 helps maintain intrinsic β-lactam resistance within the cell. To test if PBP6 and DacD play simlar roles, we deleted dacC and dacD individually, and dacC in combination with dacA, from E. coli 2443 and...

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PMID: 21719544
DOI: 10.1099/mic.0.046227-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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