Article
Human osteoclast ontogeny and pathological bone resorption.
Histology and histopathology - 1 Apr 1999
Athanasou N A, Sabokbar A
Abstract excerpt
Monocytes and macrophages are capable of degrading both the mineral and organic components of bone and are known to secrete local factors which stimulate host osteoclastic bone resorption. Recent studies have shown that monocytes and macrophages, including those isolated from neoplastic and inflammatory lesions, can also be induced to differentiate into cells that show all the cytochemical and functional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.