Article
Action of RANKL and OPG for osteoclastogenesis.
Critical reviews in eukaryotic gene expression - 1 Jan 2009
Kobayashi Yasuhiro, Udagawa Nobuyuki, Takahashi Naoyuki
Abstract excerpt
Osteoclasts develop from hematopoietic cells of the monocyte-macrophage lineage. The coculture system of osteoblasts and hematopoietic cells was devised to examine osteoclastogenesis in vitro. Experiments using the coculture system have established the concept that osteoblasts are crucially involved in osteoclastogenesis. Remarkable progress has been achieved during the last decade in our understanding the...
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