A genetic study of the human T gene and its exclusion as a major candidate gene for sacral agenesis with anorectal atresia

Abstract excerpt

Sacral agenesis is a heterogeneous group of congenital anomalies in which most cases are sporadic but rare familial forms also occur. Although one gene has been mapped to chromosome 7q36 in families with hemisacrum, associated with anorectal atresia and presacral mass, it is clear that the genetic aetiology of these disorders is complex and other genes remain to be discovered. Some years ago, the idea of T...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital gastrointestinal and neural anomalies
• Share to Congenital heart defects research
• Share to Genomic variations and chromosomal abnormalities