Article
Alcoholic pancreatitis and polymorphisms of the variable length polythymidine tract in the cystic fibrosis gene.
Alcoholism, clinical and experimental research - 1 Mar 1999
Haber P S, Norris M D, Apte M V, Rodgers S C, Norton I D, Pirola R C, Roberts-Thomson I C, Wilson J S
Abstract excerpt
BACKGROUND: The observation that only a minority of alcoholics develops clinical pancreatic disease has led to a search for a predisposing factor to the disease. One possible predisposing factor is mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene as cystic fibrosis leads to pancreatic injury. We have recently demonstrated that 15 common CFTR mutations are not found in patients with...
Topics
- Adult
- Alleles
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA
- Humans
- Pancreatitis, Alcoholic
- Polymorphism, Genetic
- Reverse Transcriptase Polymerase Chain Reaction
- Thymidine