Article
Is there an advantage to including the nucleoprotein in a rabies glycoprotein subunit vaccine?
Vaccine - 17 Mar 1999
Drings A, Jallet C, Chambert B, Tordo N, Perrin P
Abstract excerpt
The PV rabies (genotype 1) G and N proteins were produced by recombinant baculoviruses in insect cells. We tested the ability of recombinant antigens to synergistically induce an immune response and, particularly, to broaden the spectrum of Lyssavirus-neutralizing antibodies produced. Cell-free preparations of recombinant proteins caused an immune response. Recombinant rabies G protein (RRG) from infected cell...
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