Article
Partial growth hormone insensitivity--idiopathic short stature is not always idiopathic.
Acta paediatrica (Oslo, Norway : 1992). Supplement - 1 Feb 1999
Saenger P
Abstract excerpt
Heterozygous growth hormone receptor (GHR) gene defects are not a common cause of idiopathic short stature. Although some of these GHR mutations may result in relative insensitivity to growth hormone (GH) in other studies, obligate heterozygotes did not present any clinical manifestations. Althou...
Topics
- Body Height
- Child
- Child, Preschool
- Controlled Clinical Trials as Topic
- Female
- Genetic Diseases, Inborn
- Growth Disorders
- Human Growth Hormone
- Humans
- Insulin-Like Growth Factor Binding Proteins
- Male
- Mutation