Isolation of chloroform-resistant mutants of filamentous phage: localization in models of phage structure.

Abstract excerpt

Interaction of fd or M13 filamentous phage with a chloroform/water interface induces morphological change, contracting the filaments sequentially into shortened rods (I-forms), and then into spheroidal particles (S-forms). To further investigate this phage contraction, 34 and 26 chloroform-resistant isolates of fd and M13, respectively, were selected after chloroform treatment of wild-type phages at pH 8. 2 and 4...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteriophage M13
• Share to Capsid
• Share to Drug Resistance, Microbial