Article
Translational induction of heat shock transcription factor sigma32: evidence for a built-in RNA thermosensor.
Genes & development - 15 Mar 1999
Morita M T, Tanaka Y, Kodama T S, Kyogoku Y, Yanagi H, Yura T
Abstract excerpt
Induction of heat shock proteins in Escherichia coli is primarily caused by increased cellular levels of the heat shock sigma-factor sigma32 encoded by the rpoH gene. Increased sigma32 levels result from both enhanced synthesis and stabilization. Previous work indicated that sigma32 synthesis is induced at the translational level and is mediated by the mRNA secondary structure formed within the 5'-coding sequence...
Topics
- Bacterial Proteins
- Base Sequence
- Escherichia coli
- Heat-Shock Proteins
- Heat-Shock Response
- Hot Temperature
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Biosynthesis
- RNA, Bacterial
