Article
Effects of changes in membrane sodium flux on virulence gene expression in Vibrio cholerae.
Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 1999
Häse C C, Mekalanos J J
Abstract excerpt
The expression of several virulence factors of Vibrio cholerae is coordinately regulated by the ToxT molecule and the membrane proteins TcpP/H and ToxR/S, which are required for toxT transcription. To identify proteins that negatively affect toxT transcription, we screened transposon mutants of V. cholerae carrying a chromosomally integrated toxT::lacZ reporter construct for darker blue colonies on media...
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