Article
HLA antigen frequencies in end-stage idiopathic and ischaemic cardiomyopathy.
International journal of cardiology - 1 Jan 1999
Harcombe A A, Sharples L, Large S R, Wallwork J, Weissberg P L, Joysey V
Abstract excerpt
We investigated the distribution of HLA antigens among 413 patients with ischaemic heart disease or dilated cardiomyopathy referred for cardiac transplantation to determine if possession of certain HLA antigens predisposed to end-stage heart failure. Of the patients studied, 234 had ischaemic heart disease (218 males), mean age 49 years (SD 7.1) and 179 patients had dilated cardiomyopathy (150 males), mean age 39...
Topics
- Adult
- Cardiomyopathy, Dilated
- Chi-Square Distribution
- Confidence Intervals
- Female
- HLA-B Antigens
- HLA-DR1 Antigen
- HLA-DR4 Antigen
- Heart Transplantation
- Histocompatibility Testing
- Humans
- Male
- Middle Aged
- Myocardial Ischemia
- Odds Ratio
- Phenotype
