Article
A1/A2 polymorphism of glycoprotein IIIa and association with excess procedural risk for coronary catheter interventions: a case-controlled study.
Lancet (London, England) - 27 Feb 1999
Laule M, Cascorbi I, Stangl V, Bielecke C, Wernecke K D, Mrozikiewicz P M, Felix S B, Roots I, Baumann G, Stangl K
Abstract excerpt
BACKGROUND: A five-fold increase in risk of stent thrombosis in carriers of A1/A2 (Leu33Pro) polymorphism of glycoprotein Illa has been described. Whether this increased procedural risk applies to other coronary interventions is unknown. We investigated the role of A1/A2 polymorphism as a putative risk factor. METHODS: We genotyped 1000 consecutive patients with angiographically confirmed coronary-artery disease...
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