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Article

Linkage of house dust mite allergy with the HLA region.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Feb 1999

Torres-Galván M J, Quiralte J, Blanco C, Castillo R, Carrillo T, Pérez-Aciego P, Sánchez-García F

Abstract excerpt

BACKGROUND: Atopy is a multifactorial disease, the pathogenesis of which is influenced by both genetic and environmental conditions. Genes in the HLA region have been involved in the control of the IgE response. OBJECTIVE: In order to investigate whether allergy to house dust mite is associated with HLA in our population, we performed sib-pair analysis in 18 families and a case/control study of 161 non-related...

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PMID: 10071525
DOI: 10.1016/S1081-1206(10)62597-5

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