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Article

Gap junction signalling mediated through connexin-43 is required for chick limb development.

Developmental biology - 15 Mar 1999

Makarenkova H, Patel K

Abstract excerpt

During chick limb development the gap junction protein Connexin-43 (Cx43) is expressed in discrete spatially restricted domains in the apical ectodermal ridge (AER) and mesenchyme of the zone of polarising activity. Antisense oligonucleotides (ODNs) were used to investigate the role of Connexin-43 (Cx43) in the development of the chick limb bud. We have used unmodified ODNs in Pluronic F-127 gel, which is liquid...

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Identifiers

PMID: 10068470
DOI: 10.1006/dbio.1998.9171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gap junction signalling mediated through connexin-43 is required for chick limb development.PMID 10068470Read ↗

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Antisense oligonucleotides: an experimental strategy to advance a causal analysis of development.Semantic proximity Read ↗

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