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Article

Binding of the transition state analog MgADP-fluoroaluminate to F1-ATPase.

The Journal of biological chemistry - 12 Mar 1999

Nadanaciva S, Weber J, Senior A E

Abstract excerpt

Escherichia coli F1-ATPase from mutant betaY331W was potently inhibited by fluoroaluminate plus MgADP but not by MgADP alone. beta-Trp-331 fluorescence was used to measure MgADP binding to catalytic sites. Fluoroaluminate induced a very large increase in MgADP binding affinity at catalytic site one, a smaller increase at site two, and no effect at site three. Mutation of either of the critical catalytic site...

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Identifiers

PMID: 10066761
DOI: 10.1074/jbc.274.11.7052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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