Article
Biomarkers for exposure to ambient air pollution--comparison of carcinogen-DNA adduct levels with other exposure markers and markers for oxidative stress.
Environmental health perspectives - 1 Mar 1999
Autrup H, Daneshvar B, Dragsted L O, Gamborg M, Hansen M, Loft S, Okkels H, Nielsen F, Nielsen P S, Raffn E, Wallin H, Knudsen L E
Abstract excerpt
Human exposure to genotoxic compounds present in ambient air has been studied using selected biomarkers in nonsmoking Danish bus drivers and postal workers. A large interindividual variation in biomarker levels was observed. Significantly higher levels of bulky carcinogen-DNA adducts (75.42 adducts/10(8) nucleotides) and of 2-amino-apidic semialdehyde (AAS) in plasma proteins (56.7 pmol/mg protein) were observed...
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