Article
Oxidative damage to biological macromolecules in Prague bus drivers and garagemen: impact of air pollution and genetic polymorphisms.
Toxicology letters - 10 Nov 2010
Bagryantseva Yana, Novotna Bozena, Rossner Pavel, Chvatalova Irena, Milcova Alena, Svecova Vlasta, Lnenickova Zdena, Solansky Ivo, Sram Radim J
Abstract excerpt
DNA integrity was investigated in the lymphocytes of 50 bus drivers, 20 garagemen and 50 controls using the comet assay with excision repair enzymes. In parallel, 8-oxo-7,8-dihydro-2'-deoxyguanosine and 15-F(2t)-isoprostane levels in the urine and protein carbonyl levels in the plasma were assess...
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