Article
Allele-specific differences in apolipoprotein C-III mRNA expression in human liver.
Clinical chemistry - 1 Mar 1999
Esterbauer H, Hell E, Krempler F, Patsch W
Abstract excerpt
BACKGROUND: Sequence variations at the apolipoprotein (apo)C-III gene locus have been associated with increased plasma triglycerides. In particular, the S2 allele of an SstI polymorphism in the 3' untranslated region has been associated with hypertriglyceridemia in many populations. The aim of this study was to determine whether the variant S2 allele is related to increased mRNA expression in vivo. METHODS: We...
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