Article
A phenotype for genetic studies of successful cognitive aging.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2008
Silverman Jeremy M, Schnaider-Beeri Michal, Grossman Hillel T, Schmeidler James, Wang Joy Y, Lally Rachel C
Abstract excerpt
Survival from Alzheimer's disease (AD) and other dementias into late old age may be a useful phenotype for genetic studies of successful cognitive aging. To support molecular genetics studies for successful cognitive aging, we conducted a two-stage study to determine an optimal age phenotype for successful cognitive aging. First, risk of AD was evaluated, through informant interviews, in 4,794 parents and...
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