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Article

Folding of peptide models of collagen and misfolding in disease.

Current opinion in structural biology - 1 Feb 1999

Baum J, Brodsky B

Abstract excerpt

The misfolding of the triple helix has been shown to play a critical role in collagen diseases. Normal and mutated collagen triple helices can be modeled by short, synthetic peptides of varying design. NMR spectroscopy and circular dichroism studies on the assembly of these peptide models have recently been used to isolate specific steps in the folding pathway and have provided information on the alterations...

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Identifiers

PMID: 10047579
DOI: 10.1016/s0959-440x(99)80016-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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