Article
The apolipoprotein E4 allele is not associated with an abnormal lipid profile in a Native American population following its traditional lifestyle.
Atherosclerosis - 1 Feb 1999
Aguilar C A, Talavera G, Ordovas J M, Barriguete J A, Guillén L E, Leco M E, Pedro-Botet J, Gonzalez-Barranco J, Gómez-Pérez F J, Rull J A
Abstract excerpt
The apolipoprotein E4 allele is associated in industrialized countries with an elevated LDL cholesterol concentration and an increased cardiovascular risk. Our purpose in this study was to assess the influence of the genetic variation at the APOE gene locus on the lipid profile of a Native American rural population. We examined plasma lipid levels and the common apo E alleles in 142 healthy randomly selected...
Topics
- Adult
- Alleles
- Apolipoprotein E4
- Apolipoproteins E
- Female
- Genotype
- Humans
- Hypercholesterolemia
- Indians, North American
- Life Style
- Lipids
- Male
- Mexico
- Random Allocation