Article
Apolipoprotein E polymorphism association with lipoprotein profile in endogenous hypertriglyceridemia and familial hypercholesterolemia.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000
Dallongeville J, Roy M, Leboeuf N, Xhignesse M, Davignon J, Lussier-Cacan S
Abstract excerpt
Apolipoprotein (apo) E polymorphism was among the first-reported genetic polymorphisms that explained part of the normal variation in plasma cholesterol concentrations in humans. The aim of this study was to assess the influence of allelic variation at the apo E gene locus on the plasma lipoprotein profile in hyperlipidemia. The lipoprotein levels of hyperlipidemic subjects of the major apo E phenotypes (E3/2,...
Topics
- Adult
- Apolipoproteins E
- Cholesterol, LDL
- Cholesterol, VLDL
- Female
- Humans
- Hyperlipoproteinemia Type II
- Hypertriglyceridemia
- Male
- Middle Aged
- Phenotype
