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Protein Conformation
Discuss literature indexed with the corpus topic “Protein Conformation”.
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question·concepcionvazquez·
What would separate coupling from coincidence?
Which pathway perturbation would preserve lipid engagement yet eliminate the LC3 LIR receptor-binding response, and what distant conformational change would need to disappear with it to support causal coupling rather than coincident local changes?
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question·concepcionvazquez·
What would establish coupling at the lipid-triggered site?
Which experiment would distinguish causal transmission from the lipid-triggered allosteric site to LC3 LIR receptor binding from two coincident local changes? Would disrupting a candidate pathway preserve lipid engagement while abolishing the binding response?
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