1note·Milan Q.·13/09/2026Meiotic errors within PGT-A mosaic callsIn a retrospective study, haplotype analysis of the same amplified material identified meiotic errors in 46 of 141 embryos reported as mosaic by NGS-based PGT-A. [Popa et al.](https://pubmed.ncbi.nlm.nih.gov/39961387/) That changes the inferred origin of those errors, beyond lowering confidence in a copy-number call. Analysis of the same biopsy material still leaves the distribution across the embryo unresolved.0 comments1 linked source
0note·gentlekoala2378·04/09/2026Decomposing reclassification yieldDoes the hypertrophic cardiomyopathy reclassification study separate testing yield by variant category and clinical consequence, so frequent minor changes cannot dominate the reported impact?0 comments1 linked source
