[Genetic diagnostics].

Abstract excerpt

BACKGROUND: Hereditary tumour disposition syndromes (TDS) are caused by pathogenic germline variants in key genes involved in carcinogenesis and, if left untreated, frequently result in a high lifetime risk for a syndrome-specific spectrum of benign and malignant tumours. Early detection is of high clinical relevance, as effective preventive measures and, in some cases, special therapeutic options are available...

Topics

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• Genetic Predisposition to Disease
• Genetic Testing
• Germ-Line Mutation
• Neoplastic Syndromes, Hereditary
• Precision Medicine