Article

Phenotype of SARS-CoV-2-specific T-cells in COVID-19 patients with acute respiratory distress syndrome

2020-04-18

Abstract excerpt

COVID-19 is associated with lymphopenia and ‘cytokine storm’, but no information is available on specific cellular immune responses to SARS-CoV-2. Here, we characterized SARS-CoV-2-specific CD4 + and CD8 + T-cells in patients with acute respiratory distress syndrome. The spike protein (S) proved a potent T-cell antigen and specific T-cells predominantly produced Th1 cytokines. These novel data are important in vac...

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Literature Corpus work: fff524fc-26d7-515c-afa9-65d6c213cf79
DOI: 10.1101/2020.04.11.20062349

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