Loss of ARID1A Expression is Associated with Systemic Inflammation Markers and has Important Prognostic Significance in Gastric Cancer.

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The tumor suppressor gene AT-rich interactive domain 1A (<italic>ARID1A</italic>) and systemic inflammatory response (SIR) have been reported to be related to the sensitivity of immunotherapy. This study intended to explore the relationship between <italic>ARID1A</italic> expression and SIR, and to further elucidate the prognostic value of <italic>ARID1A </itali...

Topics

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• Acetylation
• CD8-Positive T-Lymphocytes
• Chemokine CXCL10
• Chromatin Remodeling and Cancer
• Histone Deacetylase Inhibitors
• Histones
• Immune Checkpoint Inhibitors
• Tumor Microenvironment

Identifiers and source

Literature Corpus work

ffbb9339-58cf-5e10-a5bd-3a8d875a6fe7

DOI

10.21203/rs.3.rs-1090858/v1