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PacBio HiFi sequence data reveal a chromosomal misassembly in the Candida parapsilosis CDC 317 reference sequence and provide the foundation for a phased diploid genome assembly

2025-12-02

Abstract excerpt

The incidence of systemic candidiasis caused by the diploid ascomycetous yeast Candida parapsilosis is increasing. Research is aimed at understanding how the yeast interacts with its human host, as well as mechanisms of antifungal drug resistance. This work describes use of highly accurate, long-read DNA sequencing technology (Pacific Biosciences HiFi) to construct collapsed haploid and phased diploid genome assem...

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Literature Corpus work: ff927f59-0d91-56c8-8164-bc8e39d5cdff
DOI: 10.1099/acmi.0.001147.v1

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