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Predictive Capacity of Mismatch Repair Status in the Use of Immune Checkpoint Inhibitors for the Treatment of Aggressive Pituitary Adenomas and Pituitary Carcinomas: Illustrative Case Report and Literature Review

2025-10-15

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<title>Abstract</title> <p>Introduction Aggressive pituitary adenomas (APAs) and pituitary carcinomas (PCs) are rare tumors that often recur despite surgery and radiation. Immune checkpoint inhibitors (ICI) present a promising treatment alternative for these tumors; however, there is a paucity of information in the literature correlating specific tumor genomics with clinical responses. Methods Our study conducte...

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Literature Corpus work
ff8895d3-e536-5df0-9b01-219710d3f4e6
DOI
10.21203/rs.3.rs-7465129/v1
Open publication

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Predictive Capacity of Mismatch Repair Status in the Use of Immune Checkpoint Inhibitors for the Treatment of Aggressive Pituitary Adenomas and Pituitary Carcinomas: Illustrative Case Report and Literature ReviewDOI 10.21203/rs.3.rs-7465129/v1
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