Article

Vildagliptin modulates the microbiota and induces an immunometabolic neuroprotective profile in type 2 diabetes

2025-05-30

Abstract excerpt

<title>Abstract</title> <p>Dipeptidyl peptidase 4 <bold>(</bold>DPP-4) inhibitors (DPP-4i) are widely used to treat Type 2 diabetes (T2D) and are known for their cardiovascular and renal safety profiles. Systematic reviews have also shown that DPP-4i are associated with reduced dementia risk via unknown mechanisms. To examine vildagliptin (DPP-4i) effects on the intestinal microbiota in T2D patients, plasma metab...

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Literature Corpus work: ff58888b-07dd-5072-a90a-976648d17122
DOI: 10.21203/rs.3.rs-6596504/v1

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